| CAS: | 2886-65-9 |
| MF: | C15H10ClFN2O |
| MW: | 288.7 |
| EINECS: | 220-748-3 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;pharmacetical;(intermediate of fludiazepam,flurazepam);Aromatics;Heterocycles;medical intermediate |
| Mol File: | 2886-65-9.mol |
 |
|
| N-desalkylflurazepam Chemical Properties |
| Melting point | 204-206°C |
| Boiling point | 454.0±45.0 °C(Predicted) |
| density | 1.39±0.1 g/cm3(Predicted) |
| Fp | 9℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 11.55±0.70(Predicted) |
| form | A neat solid |
| InChI | InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20) |
| InChIKey | UVCOILFBWYKHHB-UHFFFAOYSA-N |
| SMILES | N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NCC1=O |
| CAS DataBase Reference | 2886-65-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Norfludiazepam(2886-65-9) |
| N-desalkylflurazepam Usage And Synthesis |
| Description | Desalkylflurazepam (Item No. 18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam , flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Cav; IC50s = 55 and 37 μM for Cav1.2 and 1.3, respectively) by positively modulating GABAA receptors. It can be detected in urine, serum, and meconium by LC-MS/MS. This product is intended for research and forensic applications. |
| Chemical Properties | Light Yellow Solid |
| Uses | The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase |
| Definition | ChEBI: Desalkylflurazepam is a benzodiazepine. |
| General Description | N-Desalkylflurazepam (also known as norflurazepam, 2886-65-9) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward. |
| Mode of action | N-Desalkylflurazepam is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Advantage
In stock
Japan
