Use of miglustat
Miglustat(OGT918) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).Target: OthersMiglustat is an inhibitor of the ceramide-specific glycosyltransferase, which catalyzes the first step of glycosphingolipid biosynthesis and is currently approved for the oral treatment of type 1 GD [1]. Consumption of a standard high-fat breakfast within 30 minutes before administration of miglustat significantly reduced peak exposure but did not significantly affect the extent of systemic exposure to miglustat. The peak plasma concentration (C(max)) decreased by 36% on average following administration with food. Area under the plasma concentration-time curve (AUC(0-infinity)) showed a modest (14%) decrease with food, but the 90% confidence interval was within the acceptance limit of 80% to 125%. The median (min-max) time to C(max) (t(max)) was prolonged from 2.5 (1.0-4.0) hours in the fasted state to 4.5 (1.5-8.0) hours in the fed state, whereas the apparent terminal half-life was approximately 8 hours and not affected by food
Packing,StorageTransportation:
1. Packing: 25 kg/bag
2. Storage: Store in a dry and ventilated place, and pay attention to moisture and humidity. Long-term storage does not deteriorate, if there is caking, crushing or dissolution does not affect the use effect.
3. Transportation: This product is non-toxic and harmless, non-flammable and explosive dangerous goods. It can be transported by car, sea or train. Less carload, vehicle is not limited, agent consignment.
Transport:
1.Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
2.For mass orders, it will be delivered by air or sea.
3.Depending on your location, please allow 1-5 business days for your order to arrive.
4.For small order, please expect 3-7 days by UPS DHL EMS.
5.For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Company Profile:
We are Ouhuang Engineering Materials (Hubei) Co., Ltd.Our company mainly produces and sells various Building materials materials and various production AIDS water-based environmentally friendly resins (water-based resin powder, water-based rosin resin, water-based terpene tree, etc.), various water-based environmentally friendly latex (water-based thickened emulsion, water-based air-butyl latex, water-based butyl latex, etc.) , and various environmentally friendly additives (defoamer, thickener, antioxidant, dispersant).High-end product quality and sincere sales service are our tenets.We are willing to provide you with professional services in the areas we are familiar with and look forward to your consultation.
Our advantage:
1.Our company has a professional research team to develop building raw materials chemical products and mature technicians to create value
2.We can also meet the special customization needs of customers as well as various special packaging requirements.
3.We can also provide samples to our customers free of charge.
4.We provide commercial invoice, packing list, Bill of Lading, COA, Health Certificate and Certificate of Origin. If your market has any special requirements, please let us know.
5.Prompt delivery, as long as you confirm that the order is available in stock can be arranged within 24h.
6.Diversification of payment methods,Such as L/C, T/T, D/A, D/P, paypal, Western Union etc, and we cooperate with Sinosure many years.
FAQ:
Q: What's your MOQ ?
A: It depends on the product you buy.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
I am Mandy,
Email: sales12@hbouhuang.com
Telephone/Wechat: 0086–15629005126
Whatsapp/Skype/Telegram: 0086–15629005126
Ouhuang Engineering Materials(Hubei)Co.,Ltd
Welcome inquiry!
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