PRODUCT INFORMATION
Names
| Name | n-(2-hydroxypropyl)methacrylamide |
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| Synonym | More Synonyms |
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N-(2-HYDROXYPROPYL)METHACRYLAMIDE Biological Activity
| Description | N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1]. |
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| Related Catalog | Research Areas >> Infection Signaling Pathways >> Others >> Others |
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| In Vivo | At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition)[1]. |
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| References | [1]. Nan A, et al. N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. J Control Release. 2001 Dec 13;77(3):233-43. [2]. Hao Tang, et al. Comb-like Poly(N-(2-hydroxypropyl) methacrylamide) Doxorubicin Conjugates: The Influence of Polymer Architecture and Composition on the Biological Properties. Chinese Journal of Polymer Science volume 36, pages1225-1238(2018). |
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Chemical & Physical Properties
| Density | 1.002g/cm3 |
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| Boiling Point | 321.2ºC at 760mmHg |
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| Melting Point | 70 °C |
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| Molecular Formula | C7H13NO2 |
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| Molecular Weight | 143.18400 |
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| Flash Point | 148.1ºC |
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| Exact Mass | 143.09500 |
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| PSA | 49.33000 |
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| LogP | 0.45040 |
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| Vapour Pressure | 2.43E-05mmHg at 25°C |
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| Index of Refraction | 1.46 |
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Safety Information
| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-36/37/39 |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Company Profile
Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.
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Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.
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Contact name: Tina
Email address: Tina@fdachem.com
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