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MUSCIMOL HYDRATE Basic information
Product Name: MUSCIMOL HYDRATE
Synonyms: MUSCIMOL HYDRATE;5-(aminomethyl)-3(2h)-isoxazolonmonohydrobromide;5-(aminomethyl)-3-isoxazololmonohydrobromide;5-(aminomethyl)-3-isoxazolomonohydrobromide;5-(AMMOMETHYL)-3-ISOXAZOLOL H20;5-(AMINOMETHYL)-3-HYDROXYISOXAZOL HYDRATE;Nsc304080;MUSCIMOL HBR
CAS: 18174-72-6
MF: C4H6N2O2.BrH
MW: 195.01
EINECS:
Product Categories: Enzyme substrates;Neurochemicals
Mol File: 18174-72-6.mol
MUSCIMOL HYDRATE Structure
MUSCIMOL HYDRATE Chemical Properties
Melting point 172 °C
storage temp. 2-8°C
solubility ethanol: 1 mg/mL
form powder
color off-white
Stability: Store in freezer at -20°C
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 22-36/37/39-45
RIDADR UN 1544 6.1/PG 2
WGK Germany 3
RTECS NY3345000
MSDS Information
MUSCIMOL HYDRATE Usage And Synthesis
Description Muscimol HBr (18174-72-6) is a GABA-A receptor agonist.
Chemical Properties Tan Solid
Uses A potent but toxic structural analogue of g-aminobutyric acid (GABA), with a zwitterionic structure that can cross the blood-brain barrier.
Biochem/physiol Actions Muscimol hydrobromide is a GABAA receptor agonist.
References 1) Akhondzadeh et al. (1995), Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors; Br. J. Pharmacol., 115 527
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