| Name | MOG peptide (35-55), mouse, rat acetate |
| Description | MOG peptide (35-55), mouse, rat acetate, is a minor component of central nervous system myelin with encephalitogenic activity. It can induce CD4⁺ T cell proliferation and Th1-type immune responses, leading to relapsing-remitting demyelinating disease. It is commonly used to establish experimental autoimmune encephalomyelitis (EAE) models. |
| In vitro | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) at concentrations ranging from 0 to 50 μg/mL for 72 hours induces T cell proliferation and triggers the secretion of Th1 cytokines, including TNF-α, IL-10, IFN-γ, IL-4, and IL-5. Moreover, it also enhances the production of IgG.[1] |
| In vivo | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55) (200 μg (0.2 mL); i.p.; once, for 38 d) demonstrates encephalitogenic properties in HLA-DR2 (DRB1*1501) mice[1]. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 90.0 mg/mL (34.1 mM), Sonication is recommended.
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| Keywords | MOG peptide , mouse, rat Acetate | 149635-73-4 Free base | 149635-73-4 |
| Related Compound Libraries | Peptide Compound Library |
United States
