Mildronate Dihydrate | EP-Certified Cardiovascular API | Bulk Supplier for Cardioprotective Therapies
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🌟 Product Overview
Mildronate Dihydrate (CAS 86426-17-7) is a cardioprotective agent and structural analog of L-carnitine, primarily used to treat myocardial ischemia, angina, and improve exercise tolerance. It inhibits γ-butyrobetaine hydroxylase (BBOX1) and carnitine biosynthesis, reducing fatty acid oxidation and enhancing cellular energy metabolism under hypoxic conditions. Approved for clinical use, it is essential in cardiovascular therapeutics and metabolic research13.
✔️ Key Advantages
High Purity: ≥98% HPLC purity compliant with EP standards for pharmaceutical use15.
Solubility: White crystalline powder, highly soluble in water (>40 mg/mL) for oral or injectable formulations56.
Bulk Customization: Available in 1kg–25kg batches with COA, MSDS, and stability documentation12.
🏥 Applications
Cardiovascular Therapy: Reduces angina symptoms and improves cardiac function in ischemic heart disease13.
Metabolic Regulation: Inhibits carnitine-dependent fatty acid transport for energy metabolism modulation47.
Sports Medicine: Enhances exercise capacity in patients with cardiovascular limitations (under medical supervision)34.
📜 Quality Compliance
Certified under EP guidelines with residual solvents <10 ppm and heavy metals <20 ppm15.
Stability tested for 24 months when stored at 2-8°C in airtight, moisture-resistant packaging15.
📈 Market Trends
The global cardiovascular drug market is projected to grow at 5.3% CAGR (2025-2030), driven by rising demand for ischemia management solutions. Mildronate’s dual action on energy metabolism and cardioprotection positions it as a key therapeutic agent34.
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