| CAS: | 942-24-5 |
| MF: | C10H9NO2 |
| MW: | 175.18 |
| EINECS: |
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| Product Categories: | Heterocycle-Indole series;Indoles;Indoles and derivatives;Simple Indoles;Building Blocks;Heterocyclic Building Blocks;Heterocycles series;IndoleDerivative;Indole |
| Mol File: | 942-24-5.mol |
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| Methyl indole-3-carboxylate Chemical Properties |
| Melting point | 149-152 °C (lit.) |
| Boiling point | 306.47°C (rough estimate) |
| density | 1.1999 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 15.42±0.30(Predicted) |
| form | Solid |
| color | Light Pink |
| Water Solubility | Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water. |
| BRN | 142023 |
| CAS DataBase Reference | 942-24-5(CAS DataBase Reference) |
| Methyl indole-3-carboxylate Usage And Synthesis |
| Chemical Properties | light brown amorphous powder |
| Uses | Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II. |
| Uses | Reactant for preparation of:
Nitric oxide synthase (nNOS) inhibitorS Protein kinase c alpha (PKCα) inhibitors Inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents Kinase insert domain receptor (KDR) inhibitors Organocatalysts for the anti-Mannich reaction Very late antigen-4 (VLA-4) antagonists Inhibitors of Human 5-Lipoxygenase Serotonin 5-HT4 receptor antagonists Hyaluronidase inhibitors
Reactant for:
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| Definition | ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid. |
| General Description | Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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