Uses
Benzeneacetic acid, a-acetyl-, methyl ester can be used as a pharmaceutical raw material.
Description
Methyl 2-phenylacetoacetate is an
analytical reference standard categorized as a precursor in the
synthesis of amphetamines and methamphetamines. This product is intended
for research and forensic applications.
The Drug Enforcement
Administration is proposing the control of the chemical methyl
alpha-phenylacetoacetate (also known as MAPA; methyl
3-oxo-2-phenylbutanoate; methyl 2-phenylacetoacetate;
[alpha]-acetyl-benzeneacetic acid, methyl ester; and CAS Number:
16648-44-5) and its optical isomers as a list I chemical under the
Controlled Substances Act (CSA). Methyl alpha-phenylacetoacetate is used
in clandestine laboratories to illicitly manufacture the schedule II
controlled substances phenylacetone (also known as phenyl-2-propanone or
P2P), methamphetamine, and amphetamine and is important to the
manufacture of these controlled substances.
Description
Methyl 2-phenylacetoacetate (Item No.
28352) is an analytical reference standard categorized as a precursor in
the synthesis of amphetamines and methamphetamines. This product is
intended for research and forensic applications.
Uses
D1, D2 dopamine receptor antagonist;
butyrophenone antipsychotic and anti-emetic.
Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is
an antipsychotic, which is used to treat acute behavioral anomalies. It
helps to manage postoperative nausea and vomiting.
Endogenous κ1b opioid receptor agonist.
Preparation
Methyl phenyldiazoacetate, precursor to
cyclopropanation agents, is prepared by treating methyl phenylacetate
with p-acetamidobenzenesulfonyl azide in the presence of base.
Methyl 2-phenylacetoacetate Properties
| Melting point | 58.5-59.0 °C |
|---|
| Boiling point | 92-96 °C(Press: 0.6 Torr) |
|---|
| Density | 1?+-.0.06 g/cm3(Predicted) |
|---|
| pka | 10.67±0.46(Predicted) |
|---|
Shanghai Mifa chemical Co., Ltd. is a scientific and technological company engaged in the development, production and operation of chemical products. It is a comprehensive enterprise integrating scientific and Technological Development and mass production. It is a professional product R & D and production factory in Shanghai Province, with good product quality.
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