1. Materials information
Names
| Name | methoxypoly(ethylene glycol) |
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| Synonym | More Synonyms |
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m-PEG-OH (MW 2000) Biological Activity
| Description | m-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.08 |
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| Boiling Point | 557.1±45.0 °C at 760 mmHg |
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| Melting Point | 12 ºC |
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| Molecular Formula | C23H48O12 |
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| Molecular Weight | 516.620 |
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| Flash Point | 268 ºC |
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| Exact Mass | 516.314575 |
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| LogP | -4.38 |
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| Appearance of Characters | semisolid | White to pale yellow |
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| Vapour density | >1 (vs air) |
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| Vapour Pressure | 0.0±3.4 mmHg at 25°C |
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| Index of Refraction | 1.456 |
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| Storage condition | ?20°C |
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| Water Solubility | H2O: 50 mg/mL at 25 °C, clear, colorless |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
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| Hazard Codes | Xi |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | PE8271000 |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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