Memantine

Product Name:    Memantine

Synonyms:    AKOS BB-9600;MEMANTINE;AURORA KA-7643;TIMTEC-BB SBB002574;3,5-dimethyladamantan-1-amine HCl;1-Amino-3,5-dimethyladamantane;3,5-Dimethyl-1-aminoadamantane;1,3-Dimethylaminoadamantane

CAS:    19982-08-2

MF:    C12H21N

MW:    179.3

EINECS:    690-724-9

Product Categories:    GASTERIL;Elisa Kit-Mouse Elisa Kit

Memantine is a potent antagonist of the N-methyl-D-aspartate (NMDA) receptor. Experimentally, memantine inhibits and reverses the abnor-mal activity of a protein phosphatase (PP-2A) that leads to tauhyperphosphorylation and to neurofibrillary degeneration inAD. Memantine is effective and well toler-ated in patients with severe AD and wasapproved by the FDA for the treatment of moderate-to-severe AD.