Factory Provide 99% Raw Powder Medroxyprogesterone Acetate CAS 71-58-9
Introduction
Product Name : Medroxyprogesterone Acetate
Other name:(6-alpha)-17-(acetyloxy)-6-methylpreg-4-ene-3,20-dione;17-(acetyloxy)-6-methyl-(6-alpha)-pregn-4-ene-20-dione;
CAS No.: 71-58-9
MF: C24H34O4
MW:386.52
Appearance: White Powder
Melting Point :206-207 °C(lit.)
Boiling Point :432.7°C (rough estimate)
Density :1.0346 (rough estimate)
Storage :Keep in dark place,Sealed in dry,Room Temperature
Medroxyprogesterone 17-acetate is a synthetic progestogen.,, It prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation. Medroxyprogesterone 17-acetate reversibly blocks ovulation in rats when injected on the last day of diestrus. It also has anti-androgenic activity in rats, decreasing plasma testoster one (Item Nos. 15645 | ISO60154) levels via induction of hepatic testoster one reductase activity. Medroxyprogesterone 17-acetate exhibits immunosuppressive effects in vitro and in vivo, inhibiting the production of IFN-γ by CD2/CD3/CD28-stimulated peripheral blood mononuclear cells (PBMCs) at concentrations ≥10 nM and extending the survival of rabbit skin allografts., Injectable formulations containing medroxyprogesterone 17-acetate have been used as contraceptives.
Appplication
Medroxyprogesterone acetate (MPA) is used as birth control and as part of menopausal hormone therapy. Medroxyprogesterone acetate is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer. It is used by mouth or injection into a muscle or under the skin.
Medroxyprogesterone acetate is used for the treatment of advanced breast cancer, endometrial adenocarcinoma and renal cell carcinoma.
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