Magnolol CAS:528-43-8 Magnolia Bark Extract
Product Name:Magnolol
Synonyms:5,5'-DIALLYL-BIPHENYL-2,2'-DIOL;5,5'-DIALLYL-2,2'-BIPHENYLDIOL;5,5'-DIALLYL-2,2'-DIHYDROXYBIPHENYL;HONOKIOL(P);MAGNOLOL(SH);5',5-di-2-propenyl-(1,1'-Biphenyl)-2,2'-diol;MAGNOLOL;Magnolia officinalis Rehd.et Wils
CAS:528-43-8
MF:C18H18O2
MW:266.33
EINECS: 610-903-7
Melting point:101.5-102°
Boiling point:180°C/1mmHg(lit.)
density:1.107±0.06 g/cm3(Predicted)
storage temp.:Sealed in dry,2-8°C
solubility:ethanol: soluble1mg/mL
pka:9.49±0.43(Predicted)
form:neat
color:White to Almost white
Chemical Properties:White or off-white powder
Description
Magnolol is a bioactive compound isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases. Magnolol can activate cannabinoid (CB) receptors, behaving as a partial agonist with selectivity for the peripheral CB2 subtype (EC50 = 3.28 μM; Ki = 1.44 μM) versus central CB1 (EC50 = 18.3 μM; Ki = 3.15 μM).