PRODUCT DETAILS
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide–type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90–120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 372.7±52.0 °C at 760 mmHg |
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| Melting Point | 66-69°C |
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| Molecular Formula | C14H22N2O |
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| Molecular Weight | 234.337 |
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| Flash Point | 179.2±30.7 °C |
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| Exact Mass | 234.173218 |
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| PSA | 32.34000 |
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| LogP | 3.63 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.512 |
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| Storage condition | Store at RT |
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| Stability | Stable. Incompatible with strong oxidizing agents. |
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| Water Solubility | practically insoluble |
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Company profile
Hebei Fengqiang Trading Co.,ltd. is a high-tech enterprise engaged in the field of fine chemical products, integrating R&D, production and sales. The company has an independent R & D team, which can develop and customize any pharmaceutical raw materials with low price, high quality and first-class service! Fengqiang's products are widely exported to the United States, Russia, Canada, Australia, Europe and many other countries with double-clearance door-to-door delivery services. With honest and credible business philosophy. Harmonious development!
FAQ
Q1. What is your terms of payment?
A: T/T, details could be discussed.
A: FOB, CFR, CIF, DDU, EXW, etc.
Q2. How about your delivery time?
A: Generally, 3 to 12 days upon advance payment.
The specific delivery time depends on your detailed requirements and the quantity of your order.
Q3. Can you produce according to the samples?
A: Yes, we can offer samples or technical drawings.
Q4. What is your sample policy?
A: We could offer the sample for free charge but your esteemed company will pay the cost of freight.
Q5. Do you test all your goods before delivery?
A: Yes, we have 100% inner inspection in our own laboratory and plant before delivery.
Q6: How do you make our business long-term and good relationship?
A: 1. We keep good quality and competitive price to ensure our customers benefit ;
2. We respect every customer as our friend and we sincerely do business and make friends with them.
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