Chemical Name | levamisole |
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use | Pharmaceutical intermediate
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CAS No. | 14769-73-4 |
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Molecular Formula | C11H12N2S |
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Molecular Weight | 204.29100 |
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PSA | 40.90000 |
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LogP | 1.51960 |
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Appearance & Physical State | white to off-white crystalline powder |
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Density | 1.32g/cm3 |
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Boiling Point | 344.4ºC at 760mmHg |
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Melting Point | 230 - 233ºC |
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Flash Point | 162.1ºC |
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Storage Condition | 0-6ºC |
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Vapor Pressure | 6.61E-05mmHg at 25°C |
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Pharmacological action:
Leimidazole is a synthetic broad spectrum deworming drug. After entering the human body, leimidazole inhibits the activity of succinate dehydrogenase in the muscle of the insect body, so that fumaric acid cannot be reduced to succinic acid, sugar metabolism disorders occur, energy production is insufficient, and the muscle of the insect body is paralyzed and expelled from the body.
Clinical application:
Levamisole is commonly used to dewormer a variety of animals and is effective against both adults and larvae. It has eye-repellent parasites to many nematodes. It can be used to repel a variety of linear removal effects in birds, and can be used in pigs to repel roundworms, intestinal nematodes (strongyloides), Trichostrongylodes, and Acrostoma nematodes. It is also effective in repel roundworms, intestinal nematodes (Strongyloides), nodules (oesophagostoma nematodes), and kidney worms in the ureter (toothed Corynedes). For dogs can be used to drive away roundworms, hookworms and heartworms.