| Name | L-Ornithine |
| Description | L-Ornithine ((S)-2, 5-diaminopentanoic acid) is a non-protein amino acid. L-Ornithine is mainly used in the urea cycle to remove excess nitrogen from the body. L-Ornithine is renoprotective. L-Ornithine has antifatigue effects. |
| In vitro | METHODS: HK-2 cells were treated with L-Ornithine (100, 300 μM) for 24 hours, and ROS levels were measured using fluorescence microscopy.
RESULTS: Ornithine protected HK-2 cells from ROS production. [1] |
| In vivo | METHODS: To investigate the effect of L-Ornithine on peripheral clock gene expression, mice were orally treated with L-Ornithine (1000 mg/kg) for 3 days.
RESULTS: The phase of PER2 gene expression in liver, submandibular gland and kidney was significantly advanced in L-Ornithine treated mice. [2]
METHODS: To investigate the effect of L-Ornithine on sleep behavior, L-Ornithine was added to the diet of maternal mice, and its effect on the sleep behavior of offspring mice was observed.
RESULTS: L-Ornithine supplementation increased sleep-like behavior in mice. [3]
METHODS: To study the effect of L-Ornithine on acute necrotizing pancreatitis, rats were intraperitoneally injected with L-Ornithine (3 g/kg).
RESULTS: Severe acute necrotizing pancreatitis was induced by L-Ornithine in rats. [4] |
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : Insoluble
H2O : 50 mg/mL (378.33 mM), Sonication is recommended.
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| Keywords | Ornithine decarboxylase antizyme 1 | Ornithine carbamoyltransferase | Ornithine aminotransferase | L-Ornithine | LOrnithine | L Ornithine | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | Arginase-2 | Arginase-1 | AminoAcidsandDerivatives | Amino Acids and Derivatives | 2,5-Diaminopentanoic acid |
| Inhibitors Related | Sucrose | Aceglutamide | L-Pyroglutamic acid | Emtricitabine | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Glycerol | Thymidine | Gluconate Calcium | Chitosan oligosaccharide | 3-Indoleacetic acid |
| Related Compound Libraries | Bioactive Compound Library | EMA Approved Drug Library | Natural Product Library | Miao medicine Compound Library | Drug Repurposing Compound Library | Tobacco Monomer Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Human Endogenous Metabolite Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Gut Microbial Metabolite Library |
United States
