Factory Directly Supply L-Epicatechin CAS:490-46-0
Product Name:L-Epicatechin
Synonyms:3,3',4',5,7-PENTAHYDROXY-FLAVANE;3,3',4',5,7-PENTAHYROXYFLAVONE;3,3',4',5,7-PENTAHYDROXYFLAVAN;(2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL;(-)-epicatecho;(-)-epicatechol;(-)-EPICATECHIN;(+)-EPICATECHIN
CAS:490-46-0
MF:C15H14O6
MW:290.27
EINECS: 207-710-1
Melting point:240 °C (dec.)(lit.)
alpha:-55～-65゜(D/20℃)(c=1,CH3OH)
Boiling point:629.2 °C
density:1.593±0.06 g/cm3(Predicted)
storage temp.:-20°C
solubility:insoluble in H2O; insoluble in EtOH; ≥14.5 mg/mL in DMSO
Chemical Properties:white to light yellow crystal powde
Description
(−)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities. It scavenges DPPH radicals in a cell-free assay when used at a concentration of 5 μM. (−)-Epicatechin inhibits COX-1 (IC50 = 3.2 μM). It acts synergistically with epigallocatechin gallate to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 μM. (−)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.
China
