| Name | Kinetensin acetate(103131-69-7 free base) |
| Description | Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide. |
| In vitro | The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium[2]. |
| In vivo | Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats[2]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 10 mM, Sonication is recommended.
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| Keywords | NeurotensinReceptor | Neurotensin Receptor | Kinetensin acetate(103131-69-7 free base) | Kinetensin acetate(103131697 free base) | Kinetensin acetate(103131 69 7 free base) | Kinetensin Acetate | Kinetensin |
| Inhibitors Related | SB-657510 | Substance P 1-9 aceate | AF38469 | Meclinertant | SB 611812 | Neurotensin | SBI-553 | Neurotensin(8-13) 3TFA(60482-95-3(free base)) | SORT-PGRN interaction inhibitor 1 | (±)-AC 7954 hydrochloride | [Lys8, Lys9]-Neurotensin (8-13) acetate | Urantide acetate(669089-53-6 free base) |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Peptide Compound Library | NO PAINS Compound Library | Natural Product Library for HTS | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library |
United States
