Name | JMJD7-IN-1 |
Description | JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7. |
In vitro | JMJD7-IN-1 efficiently binds to JMJD7, with an IC50 of 3.80 μM.?JMJD7-IN-1 (72 h) inhibits the growth of T-47d, SK-BR-3, Jurkat and Hela cells, with IC50s of 9.40 μM, 13.26 μM, 15.03 μM and 16.14 μM, respectively. JMJD7-IN-1 (0.1-1000 μM) dose-dependently inhibits the activity of JMJD7, with an IC50 of 6.62 μM. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 3.64 mg/mL (10.02 mM), Sonication is recommended.
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Keywords | JMJD7-IN-1 | JMJD-7-IN-1 | JMJD7IN1 | JMJD7 IN 1 | JMJD7 | Inhibitor | inhibit | HistoneDemethylase | Histone Demethylase | cancer |
Inhibitors Related | LSD1-IN-24 | Tranylcypromine hemisulfate | Procaine | Tranylcypromine (2-PCPA) hydrochloride | GSK-LSD1 dihydrochloride | GSK-J4 | FY-21 | Daminozide | Zavondemstat | AS8351 | Procaine hydrochloride | Eicosapentaenoic Acid |
Related Compound Libraries | Glycometabolism Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Hematonosis Compound Library | Glutamine Metabolism Compound Library | Angiogenesis related Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library |