Ivermectin

$0.00 100g

$0.00 500g

$0.00 1000g

Min. Order100g
Purity99%
Cas No70288-86-7
Supply Ability20 tons
Update time2023-09-14

Wuhan Han Sheng New Material Technology Co.，Ltd

2YR

China

Chemical Properties

Product Name	Ivermectin
CAS No	70288-86-7
EC-No	274-536-0
Min. Order	100g
Purity	99%
Supply Ability	20 tons
Release date	2023/09/14

Contact me: admin06@hsnm.com.cn

Product Description

Product Name:	Ivermectin
CAS:	70288-86-7
MF:	C48H74O14
MW:	875.09
EINECS:	274-536-0
alpha	D +71.5 ± 3° (c = 0.755 in chloro form)
storage temp.	2-8°C
solubility	H2O: ≤1.0% KF
form	Powder
color	White to Off-white

Uses:

1. Ivermectin is available for controlling and treating onchocerca volvulus, and its untoward effect is lower than that of carbamazine.
2. Ivermectin can be used as a kind of antiphrastic drug and has an anthelmintic activity towards nematode, hookworm, roundworm, worm, insect and mite.

Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca)

beta-lactamase inhibitor; antibiotic

antiparasitic

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Anthelmintic (Onchocerca).

Ivermectin (Cardomec, Eqvalan, Ivomec) is a mixtureof 22,23-dihydro derivatives of avermectins B1a and B1bprepared by catalytic hydrogenation. Avermectins aremembers of a family of structurally complex antibioticsproduced by fermentation with a strain of Streptomycesavermitilis. Their discovery resulted from an intensivescreening of cultures for anthelmintic agents from naturalsources. Ivermectin is active in low dosage against awide variety of nematodes and arthropods that parasitizeanimals.
Ivermectin has achieved widespread use in veterinarypractice in the United States and many countries throughoutthe world for the control of endoparasites and ectoparasitesin domestic animals. It has been found effective forthe treatment of onchocerciasis ("river blindness") in humans, an important disease caused by the roundwormOncocerca volvulus, prevalent in West and Central Africa,the Middle East, and South and Central America.Ivermectin destroys the microfilariae, immature forms ofthe nematode, which create the skin and tissue nodules thatare characteristic of the infestation and can lead to blindness.It also inhibits the release of microfilariae by theadult worms living in the host. Studies on the mechanismof action of ivermectin indicate that it blocks interneuron-motor neuron transmission in nematodes by stimulatingthe release of the inhibitory neurotransmitter GABA.The drug has been made available by the manufacturer ona humanitarian basis to qualified treatment programsthrough the World Health Organization.

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