名称 | Isolithocholic Acid |
描述 | Isolithocholic Acid (3-Epilithocholic acid) (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic Acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate. |
体外活性 | Isolithocholic Acid at a concentration of 0.01% does not inhibit the spore germination and outgrowth in CF5 and M120 strains, but at a higher concentration of 0.1%, it significantly inhibits these processes. At a much lower concentration (0.00003%), it prevents the growth of CD196, M68, CF5, 630, and BI9 strains, while also substantially reducing toxin activity in CF5, BI9, M120, and 630 strains. Furthermore, a slightly higher concentration of Isolithocholic Acid (0.0003%) results in a significant decrease in toxin activity across all strains, with the exception of R20291 and M120[3]. |
体内活性 | Fecal Isolithocholic Acid levels significantly decrease starting from day 28 in the high fat diet (HFD) group when compared to rats on a normal diet[4]. |
存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | Chloroform : Slightly soluble Ethanol : Slightly soluble Methanol : Slightly soluble DMSO : 4.4 mg/mL (11.68 mM)
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关键字 | beta-Lithocholic acid | Isolithocholic Acid | 3b-Hydroxy-5b-cholanic acid | b-Lithocholic acid | 3beta-Hydroxy-5beta-cholanic acid |
相关产品 | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Oleamide | Glycerol | Thymidine | Naringin |
相关库 | 经典已知活性库 | 天然产物库 | 高通量筛选天然产物库 | 已知活性化合物库 | 肠道微生物代谢化合物库 | 人代谢物化合物库 |