Factory Provide Pharmaceutical Raw Material CAS No 74431-23-5 Imipenem Powder
Introduction
Product Name : Imipenem
Other name:ImipenemMonohydrate≥96%(HPLC);Imipenemhydrate;ImipenemMonohydrate(100mg);(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[Chemicalbook(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacidmonohydrate,Primaxinmonohydrate,Tienammonohydrate;
CAS No.: 74431-23-5
Molecular Formula: C12H19N3O5S
Molecular Weight: 317.36
Specification:99%
Appearance: White powder or crystal
Melting Point :193-198°C
Boiling Point :567℃(Predicted)
Storage :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Imipenem is a chemically stable thienamycin derivative with an antibacterial activity that is broader in spectrum and of greater potency than most of the third generation cephalosporins. Combination with cilastatin, an inhibitor of renal brush-border dehydropeptidase-I, increases both urinary and plasma levels of imipenem.
Application
Imipenem has antibacterial effects on Gram-positive and negative aerobic and anaerobes. The antibacterial spectrum includes Streptococcus, Staphylococcus aureus, Escherichia coli, Klebsiella, some strains of Acinetobacter, Haemophilus bacillus, Proteus, Serratia, Pseudomonas aeruginosa, etc.
Clinically, it is mainly used for respiratory tract infections, biliary tract infections, urinary system and abdominal cavity infections, skin and soft tissues, bones and joints, gynecological infections caused by gram-positive bacteria, negative bacteria, and anaerobic bacteria.
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