1. Product information
Names
| Name | Ibotenic acid |
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| Synonym | More Synonyms |
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Ibotenic acid Biological Activity
| Description | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. |
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| Related Catalog | Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Natural Products >> Acids and Aldehydes Research Areas >> Neurological Disease |
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| Target | NMDA receptor[1] |
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| In Vitro | Ibotenic acid (Ibo) is capable of acting at both NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is involved in Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3±8 μM (n=5) as measured by release of lactate dehydrogenase to the culture media[1]. |
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| References | [1]. Zinkand WC, et al. Ibotenic acid mediates neurotoxicity and phosphoinositide hydrolysis by independent receptormechanisms. Mol Chem Neuropathol. 1992 Feb-Apr;16(1-2):1-10. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 458.8±45.0 °C at 760 mmHg |
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| Melting Point | 141-147 °C |
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| Molecular Formula | C5H6N2O4 |
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| Molecular Weight | 158.112 |
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| Flash Point | 231.3±28.7 °C |
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| Exact Mass | 158.032761 |
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| PSA | 109.58000 |
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| LogP | -1.07 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.610 |
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| Storage condition | -20°C |
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MSDS
Ibotenic acid MSDS(Chinese) |
Safety Information
| Symbol | 
GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301 |
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| Precautionary Statements | P301 + P310 |
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| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
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| Hazard Codes | T: Toxic; |
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| Risk Phrases | R23/24/25 |
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| Safety Phrases | S45-S38-S36/37/39-S28A-S22 |
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| RIDADR | 1544 |
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| RTECS | NY2100000 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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