HSP90-IN-19 is a potent inhibitor of heat shock protein 90 (Hsp90), exhibiting inhibitory activity with an IC50 of 0.27 μM. It is utilized in the research of viral infections, neurodegenerative diseases, and inflammation [1].
In vitro
HSP90-IN-19 exhibits potent Hsp90 inhibitory activity with an IC50 value of 0.27 μM [1]. At concentrations of 40, 8, 1.6, 0.32, and 0.064 μM over 48 hours, HSP90-IN-19 demonstrates antiproliferative effects on MCF-7, SW480, A549, HL60, and SMMC-7721 cell lines, with IC50 values of >40 μM, >40 μM, >40 μM, 16.95 μM, and >40 μM, respectively [1].
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