| Name | Hispolon |
| Description | Hispolon is a polyphenol. Hispolon can be isolated from Phellinus linteus. Hispolon exhibits anticancer, antidiabetic, antiviral, hepatoprotective, antioxidant, and anti-inflammatory activities. |
| In vitro | Hispolon (25 and 50 μM, 2-8 h) reduces the expression of the G1–S transition-related protein cyclin D4 while increasing the expression of the CDK inhibitor p21. Hispolon (25 and 50 μM, 24-72 h) induces G2/M cell cycle arrest, apoptosis, and inhibits cell viability and migration in U87MG cells[2]. |
| In vivo | Hispolon (5 and 10 mg/kg, s.c.) reduces tumor growth in DBTRG xenograft mice[3]. Hispolon (2.5-10 mg/kg, i.p.) attenuates LPS-induced acute lung injury in mice[4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 112.5 mg/mL (510.85 mM), Sonication and heating to 70℃ are recommended.
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| Keywords | HISPOLON(P) | Hispolon |
| Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Metronidazole | Doxycycline | Penicillin G potassium | EDTA copper(II) disodium salt | Ethyl acetoacetate | Ampicillin |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Bioactive Compound Library | Anti-Viral Compound Library | Natural Product Library | Microbial Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |