Hexarelin belongs to the category of drugs known as GHRP’s, which are also sometimes referred to as GH secretagogues. They include GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Hex’s primary function is to stimulate the pituitary gland to produce more growth hormone. Like the other GHRPs, it has a 2-fold mechanism of action, in that it causes an increase in GH through amplifying the natural growth hormone releasing hormone signal transduction pathway, as well as by suppressing the actions of Somatostatin.
Hexarelin demonstrates several unique characteristics which differentiates it from other GHRP’s. Most notably, Hexarelin has been shown to be the most potent GH releaser on a mcg to mcg basis, outperforming the other drugs in its class.
It has also been shown to result in a more rapid rate of desensitization in comparison to the other GHRP’s, although the rate and extent at which desensitization progresses is often a topic of misunderstanding. Common dosing guidelines have frequently advised that researchers discontinue administration after just 2 weeks of use, suggesting that further experimentation would result in an insignificant GH spike, in response to this increased desensitization.
Hexarelin Applications:
Hexarelin is considered to be the strongest peptide stimulating GH secretion. With its use, the increase in cortisol and prolactin levels is also high enough. GHRP-2 is less strong than Hexarelin, but the increase in cortisol and prolactin levels is less too. GHRP-6 is less strong than GHRP-2, but when used in dosage up to 100mcg, it has no influence on the levels of cortisol and prolactin, and in dosage more than 100mcg, the increase in cortisol and prolactin levels is modest
Hexarelin is a peptide structurally similar to GHRP-6, which stimulates secretion of endogenous GH. Hexarelin has the majority of synthetic GH effects, but these effects are less evident with Hexarelin than with GH. The main effects of Hexarelin include increase of strength, growth of new muscle fibers, improving of vessels state, reduction of fat mass. The main difference of Hexarelin from GHRP-6 is that Hexarelin does not promote appetite, because it does not increase the level of ghrelin in the body.
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