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Cosmetic Material Hexamidine Diisethionate/Factory supply
Hexamidine diisethionate: A broad-spectrum water-soluble cationic antimicrobial agent effective against bacteria, fungi, and yeast. It can serve as a multifunctional preservative and skin disinfectant, gaining increasing application in the cosmetics industry due to its excellent anti-acne, oil control, anti-irritation, and anti-dandruff properties.
INCI Name: Hexamidine diisethionate
CAS Number: 659-40-5
Molecular Formula: C24 H38 N4 O10 S2
Molecular Weight: 606.72
Regulatory Status: Approved for use in the USA, EU, Australia, Canada, and China.
Antimicrobial Properties:
Hexamidine exhibits strong antimicrobial and bactericidal activity against:
1. Gram-positive bacteria: Staphylococcus, Micrococcus, Streptococcus, Bacillus, Propionibacterium, and Clostridium.
2. Gram-negative bacteria: Escherichia coli, Proteus, Klebsiella, Salmonella, Serratia, and Pseudomonas.
3. Fungi: Aspergillus, Penicillium, Actinobacteria, Rhizopus, and Trichophyton.
4. Yeasts: Malassezia and Pityrosporum.
The antimicrobial activity of hexamidine diisethionate varies under different conditions:
1. Concentration and contact time of the antimicrobial agent.
2. Number of microorganisms.
3. Nature and virulence of the microorganisms.
4. Characteristics of the growth medium.
Cosmetic Applications:
Hexamidine diisethionate is suitable for incorporation into cosmetics and hygiene products such as emulsions, masks, gels, aqueous solutions, alcoholic solutions, foam formulations, and sprays.
1. Microbial inhibition (preservative): It is recommended that each cosmetic formulation be studied individually.
2. Skin and hair disinfectant, for instance: care for oily and/or acne-prone skin, due to its antimicrobial activity against specific strains like Propionibacterium acnes; it can inhibit the lipase activity of Propionibacterium acnes; has indirect anti-irritation effects (slowing down triglyceride hydrolysis from sebaceous glands); anti-dandruff care (effective against Malassezia); and in deodorant products.
China
