Harmine Introduction
Definition
Harmine is a naturally occurring β-carboline alkaloid found in plants such as Peganum harmala (Syrian rue) and Banisteriopsis caapi. It is known for its psychoactive and pharmacological properties.
Function
Harmine acts as a reversible monoamine oxidase A (MAO-A) inhibitor, which helps prevent the breakdown of neurotransmitters like serotonin and dopamine. It also exhibits antioxidant, anti-inflammatory, and neuroprotective effects.
Applications
Harmine is widely used in pharmaceutical research, especially for its potential in neurodegenerative disease treatment, cancer therapy, and mental health applications. Additionally, it is utilized in biochemical studies and traditional medicine formulations.