Chinese name: (R)-(-) -2-phenylglycine methyl ester
English name: H-D-PHG-OME HCL
CAS: 19883-41-1
EINECS number: 243-399-9
Molecular formula: C9H12ClNO2
MDL number: MFCD00137487
Molecular weight: 201.65
Melting point: 189-191 °C(lit.)
Specific rotation: -118o (C=1 IN H2O)
Storage conditions: 2-8°C
Solubility: Soluble in Chloroform, Dichloromethane, baton rouge Acetate, DMSO, Acetone, etc.
Form: powder crystal
Color: White to almost white
optical activity: [α]20/D 118°, c = 1 in H2O
Detection method: T
BRN: 3915654
InChI: InChI=1/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7; / h2-6, 8 H, 10 h2, h3; 1H/t8-; /s3
InChIKey: DTHMTBUWTGVEFG-DDWIOCJRSA-N
SMILES: C (OC) (= O) @ H [C] (C1 = CC = CC = C1) n. [H] Cl | & 1:4, r |
use
D-phenylglycine methyl ester is an important intermediate in the synthesis of cefaclor and ampicillin. Cefaclor and ampicillin are semi-synthetic second-generation cephalosporins with antibacterial spectrum and antibacterial activity similar to cefazolin. They are mainly used in the treatment of otitis media, lower respiratory tract infection, urinary tract infection, skin and skin tissue infection, and can inhibit all Haemophilus influenzae, including ampicillin resistant strains.