GH-releasing
peptides (GHRPs) are synthetic peptides that like GHRH act directly on
pituitary somatotrophs to stimulate GH release. GHRP-2, an
investigational drug, is one of the most potent members of the GHRP
family. It has been shown to be effective in adults via the oral and
intranasal as well as the iv route of administration.
Growth
Hormone Releasing Peptide-2 Synthetic is a single, non-glycosylated
polypeptide chain containing 6 amino acids, having a molecular mass of
817.9 Dalton and a Molecular formula of C45H55N9O6.
Pralmorelin,
also known as Growth hormone-releasing peptide 2 or GHRP-2, is an
orally-active, synthetic peptide analogue of met-enkephalin that acts as
a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to
selectively stimulate the ghrelin receptor and cause growth hormone
release. Pralmorelin (GHRP-2) has been used clinically for the
assessment of growth hormone deficiency (GHD), It has also been shown to
have anti-inflammatory activity.
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