| Name | Garcinone C |
| Description | Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers. |
| In vitro | Garcinone C is active against both of pathogenic (MIC =100 μg/ml) and non-pathogenic leptospira (MIC = 200 μg/ml)[1]. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3, and CDK7. Garcinone C significantly inhibits cell viability of the human nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1, and HONE1 in a time‑ and dose‑dependent manner[2]. |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | STAT3 | STAT | Inhibitor | inhibit | Garcinone C | Cyclin dependent kinase | CDK7 | CDK | ATR | ATM/ATR | ATM and RAD3 related | ATM | Ataxia telangiectasia mutated | Antifection | AChR |
| Inhibitors Related | Adiphenine hydrochloride | HODHBt | Acetylcholine | Urethane | Ribavirin | Balsalazide disodium dihydrate | Nifuroxazide | L-Lysine | Abemaciclib | Niclosamide | Choline chloride | Sodium Oxamate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Immunology/Inflammation Compound Library | Anti-infective Natural Product Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |