1. Materials information
Names
| Name | 9H-fluoren-9-ylmethyl N-[2-(2-hydroxyethoxy)ethyl]carbamate |
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| Synonym | More Synonyms |
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Fmoc-N-amido-PEG2-alcohol Biological Activity
| Description | Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.221g/cm3 |
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| Boiling Point | 547.8ºC at 760 mmHg |
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| Molecular Formula | C19H21NO4 |
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| Molecular Weight | 327.37400 |
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| Flash Point | 285.1ºC |
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| Exact Mass | 327.14700 |
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| PSA | 67.79000 |
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| LogP | 2.92490 |
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| Vapour Pressure | 7.81E-13mmHg at 25°C |
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| Index of Refraction | 1.588 |
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| Storage condition | 2-8°C |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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