| Name | Flavin adenine dinucleotide |
| Description | Flavin adenine dinucleotide (FAD) is a REDOX cofactor and protein cogroup involved in various metabolic reactions. |
| In vitro | Characterized by an additional polymer-type redox reaction, Poly(Flavin adenine dinucleotide, FAD) is a highly effective electrocatalyst for NADH oxidation. Operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) exhibits an electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes demonstrate dramatically improved stability and are the most advantageous NADH transducers for analytical chemistry[2]. |
| In vivo | Administered intravenously at a dose of 2 mg/kg, Flavin adenine dinucleotide significantly cancels the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). The effect of CPZ on canine heart mitochondria is nullified by Flavin adenine dinucleotide. Following the injection of Flavin adenine dinucleotide, the dogs experience a transient hypotension within 10 minutes, after which their blood pressures recover to the initial level. Additionally, Flavin adenine dinucleotide prevents mitochondrial dysfunction induced by chlorpromazine[1]. |
| Storage | keep away from direct sunlight,store at low temperature | store at 4°C | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 125 mg/mL (159.12 mM), Sonication is recommended.
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| Keywords | Flavin adenine dinucleotide | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Natural Product Library for HTS | Human Endogenous Metabolite Compound Library Plus | Bioactive Compounds Library Max | Human Metabolite Library |
United States
