✨ Fexuprazan Hydrochloride (CAS 1902954-87-3) | High-Purity Potassium-Competitive Acid Blocker (P-CAB) ✨
🧪 Product Overview
Fexuprazan Hydrochloride (CAS 1902954-87-3), also known as Abeprazan HCl, is a potent potassium-competitive acid blocker (P-CAB) with the molecular formula C₁₉H₁₈ClF₃N₂O₃S and a molecular weight of 446.87. This white to light-yellow crystalline powder (purity ≥98%) is designed for acid-related gastrointestinal disorder treatment, offering rapid and sustained suppression of gastric acid secretion. It acts by inhibiting H+/K+-ATPase in gastric parietal cells, making it a superior alternative to traditional proton pump inhibitors (PPIs) with faster onset and longer duration.
Key Functions:
Treats gastroesophageal reflux disease (GERD) and peptic ulcers.
Enhances Helicobacter pylori eradication therapy efficacy.
Serves as a pharmaceutical intermediate for advanced formulations.
Target Industries: Pharmaceutical manufacturing, clinical research, and biotechnology.
⭐ Key Advantages
| 🔹 Ultra-High Purity | 🔹 Flexible Packaging | 🔹 Stability |
|---|
| ≥98% HPLC/EP-certified | 1g to 25kg bulk options | Stable at -20°C, moisture-proof |
| Batch-specific COA | Tamper-evident packaging | 24-month shelf life |
🏭 Applications
GERD Management: Oral tablets or capsules for chronic acid reflux relief.
Peptic Ulcer Therapy: Combined with antibiotics for H. pylori eradication.
Drug Development: Intermediate for novel P-CAB formulations and bioavailability studies.
📊 Quality Assurance
Testing Standards: Complies with USP/EP pharmacopeial guidelines.
Analytical Validation: HPLC, NMR, and LC-MS for identity and impurity profiling.
Certifications: ISO 9001 and GMP compliance for pharmaceutical-grade production.
📈 Market Insights
The global GERD treatment market is projected to reach $6.8 billion by 2030, driven by rising prevalence of acid-related disorders and demand for non-PPI therapies. Fexuprazan is gaining traction in Asia-Pacific due to cost-effective manufacturing and expanding healthcare infrastructure.
China
