Description: Esomeprazole Magnesium is the magnesium salt form of a benzimidazole with selective and irreversible proton pump inhibitor activity. In the acidic compartment of parietal cells, omeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. It is primarily used clinically to treat digestive system disorders such as gastric ulcers, duodenal ulcers, and gastroesophageal reflux disease caused by excess gastric acid secretion.
Related CAS No.: 161973-10-0 (Esomeprazole magnesium); 217087-09-7 (Esomeprazole magnesium trihydrate); 119141-88-7 (Esomeprazole)
Synonym: Esomeprazole magnesium trihydrate; (s)-omeprazole magnesium trihydrate; Omeprazole; Omeprazole Magnesium; Omeprazole Sodium; Prilosec; Esomeprazole magnesium; Prilosec OTC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Molecular Formula: C34H38MgN6O7S2
Molecular Weight: 731.14 g/mol
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Store in dry place, avoid direct sunlight.
Solubility: Slightly soluble in water, soluble in methanol,practically insoluble in heptane.
Shelf Life: >2 years if stored properly
HS Code: 2933990099
China
