1. Materials information
Names
| Name | erythrosin B |
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| Synonym | More Synonyms |
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erythrosin B Biological Activity
| Description | Erythrosin B is an artificial dye widely used in the food and textile industries. Erythrosin B is also a novel photosensitizer which has been used to develop animal models. |
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| Related Catalog | Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others |
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| In Vitro | Only the two highest concentrations of Erythrosin B tested (50.0 and 70.0 μg/mL) are significantly different (p<0.05) from the vehicle control group when the Tail Moment and Tail Intensity, which represent the extent of DNA damage, are analyzed. Results show increased micronuclei (MNi) frequencies at six of the seven Erythrosin B concentrations (0.2 to 70.0 μg/mL) when compare to vehicle control group[1]. |
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| Cell Assay | The alkaline single-cell gel electrophoresis assay (comet assay) is performed. Briefly, 2×105 HepG2 cells are seeded in a 24-well plate for 24 h. The cells are then treated with Erythrosin B at 0.1, 0.2, 2.0, 10.0, 25.0, 50.0 or 70.0 μg/mL (final concentration) for 4 h; vehicle control (0.7% DMSO) and positive control (doxorubicin0.3 μg/mL) treatments are also performed. The HepG2 cell suspension is mixed with 37°C low-melting point agarose and transferred to normal-melting point agarose-coated slides. One hundred randomly chosen nucleoids are analyzed per treatment, and a total of three independent experiments are performed[1]. |
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| References | [1]. Chen W, et al. Establishing an experimental rat model of photodynamically-induced retinal vein occlusion using erythrosin B. Int J Ophthalmol. 2014 Apr 18;7(2):232-8. [2]. Chequer FM, et al. Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells. Food Chem Toxicol. 2012 Oct;50(10):3447-51. |
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Chemical & Physical Properties
| Density | 0.98 |
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| Boiling Point | 693.2ºC at 760 mmHg |
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| Melting Point | >300ºC (Decomposes) |
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| Molecular Formula | C20H6I4Na2O5 |
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| Molecular Weight | 879.856 |
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| Flash Point | 373ºC |
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| Exact Mass | 879.618896 |
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| PSA | 81.65000 |
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| LogP | 6.96060 |
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| Vapour Pressure | 2.22E-16mmHg at 25°C |
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| Storage condition | Store at +5°C to +30°C. |
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| Water Solubility | 100g/l |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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