| Name | Ermanin |
| Description | Ermanin, a flavonoid isolated from Tanacetum microphyllum, inhibits platelet aggregation and exhibits anti-tuberculosis, anti-viral/bacterial, and potential anti-HIV-1 activities. It has anti-inflammatory properties through the inhibition of iNOS and COX-2 expression and is effective at lower concentrations in inhibiting Dione juno larvae. |
| In vitro | Ermanin (3.25, 6.25, 12.5, and 25 μM) on modulation of LPS-induced iNOS and COX-2 expression in RAW 264.7 cells. Ermanin decreased LPS-induced COX-2 and iNOS expression by 94 ± 0.5% and 94 ± 0.5% with IC50 were 1.68 μM and 6.70 μM, respectively.[1] |
| Storage | Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (318.18 mM), Sonication is recommended.
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| Keywords | tuberculosis | PGE | NOS | NO Synthase | iNOS | InfluenzaVirus | Influenza virus | HIVProtease | HIV-1 | HIV Protease | Ermanin | COX-2 | Bacterial |
| Inhibitors Related | Neomycin sulfate | Emtricitabine | Chitosan hydrochloride (80%-90% deacetylated) | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hyaluronic acid sodium (MW 20 kDa) | Trometamol | Gluconate Calcium | Dimethyl sulfoxide | Sodium diacetate | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Polyphenolic Natural Product Library | Bioactive Compound Library | Pain-Related Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Miao medicine Compound Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Anti-infective Natural Product Library | Ancient Chinese Classical Formulas Compound Library |