DTRIM24 NEW

           Product item

 dTRIM24

         CAS number

 2170695-14-2

        Molecular weight

 1113.3

        Molecular formula

  C55H68N8O13S2

        Specification

  5mg，10mg，25mg，100mg，500mg，1g,10g

       Traits

  White to off-white powder              

       Design file

  HNMR/HPLC/COA                

      Storage conditions

  store at low temperature,keep away from direct sunlight　|　Powder: -20°C for 3 years | In solvent: -80°C for 2 years               

       Delivery

   3-5 days              

        Solubility

Ethanol: insoluble

DMSO: 90.0 mg/mL (80.8 mM ), Need ultrasonic

( < 1 mg/mL refers to the product slightly soluble or insoluble )             

         References

1. Gechijian LN, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018 ; 14(4):405-412.

2. Huang JH, et al. Bioinspired PROTAC-induced macrophage fate determination alleviates atherosclerosis. 2023 ; 1-153. Han M, et al. Pharmacological targeting of Tripartite Motif Containing 24 for the treatment of glioblastoma. J Transl Med. 2021 ; 19(1):505.

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