| Name | DMBA |
| Description | DMBA (7,12-Dimethylbenz[a]anthracene) is a carcinogenic polycyclic aromatic hydrocarbon (PAH) that can be used to induce animal models of leukemia, liver cancer, breast cancer, skin cancer, and lung cancer. It is also capable of inducing programmed cell death (apoptosis) in A20.1 murine B-cell lymphoma. |
| In vivo | DMBA (0-150 mg/kg, oral administration) induces a decrease in spleen weight and a reduction in the total number of lymphocytes recovered from the spleen in C57BL/6 mice. This model can be used to establish induced cancer models such as skin carcinogenesis, breast cancer, and lung cancer[5]. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 2 mg/mL (7.8 mM), Sonication and heating are recommended.
DMSO : 23.18 mg/mL (90.43 mM), Sonication is recommended.
Acetone : 15 mg/mL (58.52 mM), Sonification is recommended.
DMF : 20 mg/mL (78.02 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 1.5 mg/mL (5.85 mM), Sonication is recommeded.
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| Keywords | Apoptosis |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Acetylcysteine | L-Glutamic acid monosodium salt monohydrate | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Hematonosis Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
United States
