Product Details:
Product Name | Dienogest
|
CAS NO. | 65928-58-7 |
Appearance | Pale yellow solid |
Purity | 99% |
Melting point | 210-214ºC |
Boiling point | 549.0±50.0 °C at 760 mmHg |
Density | 1.2±0.1 g/cm3 |
Usge | Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Target: progesterone receptor agonistDienogest is an orally active synthetic progesterone (or progestin). It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinylated progestin which is structurally related to testosterone [1]. Complete sperm suppression was observed in rats sacrificed either 60 or 90 days after dienogest (DNG)+ testosterone undecanoate (TU) administration, for two injections at 45-day interval. The neutral α-glucosidase activity in these treated rats remained in the normal range. Germ cell loss due to apoptosis was frequently observed both after 60 or 90 days of combination treatment. Significant decline in serum gonadotropin and testosterone, both serum and intratesticular levels, were observed in the treated rats. Following stoppage of treatment (given at 45-day interval) after two (0 and 45 days) or three injections (0, 45 and 90 days), complete restoration of spermatogenesis was observed by 120 and 165 days, respectively [2].Clinical indications: Adenomyosis; EndometriosisFDA Approved Date: 1995 Toxicity: weight gain; increased blood pressure; breast tenderness and nausea |
Packing & shipping
Company Profile
Yisheng Technology (Hefei) Co., Ltd. is a high-tech enterprise engaged in the area of chemical products. Our company’s main products includes pharmaceutical intermediates, plant extracts, chemical reagent, animal pharmaceutical, agrochemical intermediates, antibiotic etc..
We have import and export authority. Our products have been exported to more than 30 countries in the world. Based on the advantage of both trade and manufacture, we have been strictly managing to make the whole trade process provide customers with all-round services such as R&D, quality control, logistics and so on. We firmly believe that quality is the life of our company and that customer’s success is our success.
Payment methods:
Why Choose Us
1. Quality is our culture. We cooperate with research institutions,strictly control the process from raw material to finished product
2. Time is the gold.Fast shipment by reputed shipping line.
3. Customer comes first. We provide reasonable price, high quality product and prompt shipment.
4. Full experience of large numbers containers loading in Chinese sea port.
FAQ
Q1:How is your quality control?
A:From the very beginning to the very end, National Commodity Inspection and Testing Bureau, Authority Third-party Testing institution, QA, ISO, Guarantee our quality.
Q2:Can you provide OEM service?
A:Yes. Sure. More details if the OEM service please contact us at any time.
Q3:What payment method do you support? and logistics?
A:We support Paypal, wire T/T and credit card. We will choose express or logistics according to your quantity.
Q4:What is your MOQ?
A:Our Moq is 1 kg .
Q5:How to confirm the Product Quality before placing orders?
A:You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples.