Description of Deoxyribonuclease from Watson Biotechnology Co., Ltd
Basic Information of Deoxyribonuclease |
Product Name | Deoxyribonuclease |
CAS NO. | 9003-98-9 |
Apperance | White powder |
Assay | 2183μ/mg |
Pacakge | 10G/100G/Bag |
MOQ | 10G |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Watson |
Specifications(COA) of Deoxyribonuclease DNaseCAS 9003-98-9 DNA Enzyme I
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | Off-white crystall powder | Conform |
PH | 5.5 ～ 7.5 | 5.95 |
Solution clarification | Should be clear | Clear |
Loss on Drying | ≤5.0% | 2.38% |
Residue on Ignition | ≤1.0% | 0.2% |
Titration | ≥400μ/mg | 2183μ/mg |
Conclusion | QUALIFIED. |
Deoxyribonuclease (DNase) is an enzyme that catalyzes the hydrolytic cleavage of DNA into smaller components. There are several applications of DNase in both research and clinical settings:
1. Molecular Biology and Biotechnology:
- DNA Digestion in Experiments: DNase is commonly used to degrade DNA in samples where RNA isolation is needed, such as in RNA extraction procedures. By removing DNA, researchers can ensure that subsequent analyses are specific to RNA.
- Eliminating Contaminating DNA: DNase is used to remove contaminating DNA from various biological samples, including RNA samples and protein preparations, to ensure accurate experimental results.
- Footprinting Assays: DNase I is used in DNase I footprinting assays to study protein-DNA interactions. The enzyme cleaves DNA not protected by bound proteins, allowing researchers to identify binding sites.
2. Clinical and Therapeutic Applications:
- Cystic Fibrosis Treatment: In cystic fibrosis, DNase I (specifically recombinant human DNase I, known as dornase alfa) is used as a therapeutic agent. It helps to break down the thick mucus in the lungs by degrading the DNA released from degenerating neutrophils, improving lung function and reducing the risk of infections.
- Reducing Clot Formation: DNase has potential applications in preventing and treating thrombosis, as DNA from neutrophil extracellular traps (NETs) can contribute to clot formation. DNase can break down these DNA components and reduce clotting risk.
3. Genetic Engineering and DNA Manipulation:
- In Vitro Transcription Systems: DNase is used to remove template DNA after the synthesis of RNA to avoid contamination.
- DNA Removal in Cell Culture: It is used in cell cultures to eliminate extracellular DNA, which may interfere with certain experiments, such as transfection efficiency studies or assays requiring nucleic acid-free conditions.
4. Forensic Science:
- Sample Purification: DNase is used to purify samples by removing DNA contaminants, ensuring that only the desired nucleic acid is present for analysis, such as in RNA profiling or when isolating specific RNA species from a mixture.
Overall, DNase enzymes play a crucial role in scientific research, medicine, and biotechnology by enabling the precise manipulation and analysis of nucleic acids.
FAQ From Watson Biotechnology Co., Ltd |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
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Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
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Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
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Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
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Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
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Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance.
With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy.
At Watson Biotechnology, we pride ourselves on our cutting-edge facilities and state-of-the-art technology, which enable us to deliver superior products that cater to a diverse range of needs across various sectors. Our dedication to continuous improvement and customer satisfaction drives us to maintain stringent quality control processes and foster an environment of innovation and growth.
Watson Biotechnology Co., Ltd is a professional manufacturer which provide Deoxyribonuclease with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Deoxyribonuclease.
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