| Name | [D-Trp34]-Neuropeptide Y Acetate |
| Description | [D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats. |
| In vitro | [D-Trp34]-Neuropeptide Y Acetate exhibits pKi values of 6.49, 5.43, 7.08, 7.53, 6.55, 5.95, 6.85, 7.41 for hY1, hY2, hY4, hY5, rY1, rY2, rY4, rY5 in CHO cells. [D-Trp34]-Neuropeptide Y Acetate exhibits pEC50 values of 6.44, <6, 6.28,7.82 for rY1, rY2 in CHO cells and rY4, rY5 in HEK-293 cells[1]. |
| In vivo | [D-Trp34]-Neuropeptide Y Acetate (0, 8 and 16 μg/rat; I.C.V) stimulats food intake to the same extent in both lean and obese rats 1 h after injection at a dose of 16 μg in male Zucker rats[2]. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | NeuropeptideYReceptor | Neuropeptide Y Receptor | neuropeptide Y (NPY) Y5 receptor | 153549-84-9 Free base | 153549-84-9 | [D-Trp34]-Neuropeptide Y Acetate |
| Inhibitors Related | HT-2157 | Galanin (1-16), mouse, porcine, rat | L 152804 | GW438014A | SF-22 | JNJ-31020028 | DF-1012 FA | Galantide acetate | AR-M 1896 Acetate | AC-099 hydrochloride | Pancreatic Polypeptide (human) acetate | M871 acetate |