| Name | Cyfluthrin |
| Description | Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests. |
| In vitro | Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. Cyfluthrin increased significantly gene expressions of apoptosis, proinflammation and oxidative stress (Bax, Bcl-2, Casp-3, BNIP3, AKT1, p53, APAF1, NFκB1, TNFα and Nrf2) mediators. In the most genes, the mRNA levels induced by cyfluthrin were partially reduced by MEL (1 μM)[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Chloroform : Slightly soluble DMSO : 55 mg/mL (126.64 mM), Sonication is recommended.
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| Keywords | veterinary medicine,agriculture | SodiumChannel | Sodium Channel | ReactiveOxygenSpecies | Reactive Oxygen Species | Nav1.8 channel | Na+ channels | Na channels | insecticide,stored product | Inhibitor | inhibit | grasshopper,pest,pyrethroid | Cyfluthrin |
| Inhibitors Related | Ethoxyquin | Cysteamine hydrochloride | Phenytoin sodium | L-Ascorbic acid | Valproic Acid | Glucosamine | L-Cystine | (-)-Epigallocatechin Gallate | Coenzyme Q10 | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Arecoline |
| Related Compound Libraries | Pesticide Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Anti-Ovarian Cancer Compound Library | Neuroprotective Compound Library | Tobacco Monomer Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Liver Cancer Compound Library |