Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt NEW

$2.00 25KG

$4.00 5KG

$6.00 1KG

Min. Order1KG
Purity99%
Cas No862772-11-0
Supply Abilityg-kg-ton
Update time2025-07-28

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

VIP1Y

China

Chemical Properties

Product Name	Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt
CAS No	862772-11-0
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	g-kg-ton
Release date	2025/07/28

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

Modify Date: 2024-01-13 13:52:32

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt structure	Common Name	Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt
	CAS Number	862772-11-0	Molecular Weight	578.64100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C24H34N8O7S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Purity		Quantity		Budget		Inquiry

Use of Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) is a cyclic RGD peptide which has high affinity to αvβ3. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].

Properties
Spectrum

Name	Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl)
Synonym	More Synonyms

Description	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) is a cyclic RGD peptide which has high affinity to αvβ3. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	αvβ3
In Vitro	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM, 24 h) down-regulates the transcription factors Oct 4, Sox 2 and Nanog of mESCs[1]. Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM) inhibits integrin gene expression mESC-col I (type I collagen) constructs[1]. Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM)-treated mESCs leads to the formation of aggregates and detachment from the surface[1]. RT-PCR[1] Cell Line: MESCs Concentration: 0.5 mM Incubation Time: 24 h Result: Down-regulated Oct 4, Nanog, Sox 2 by 99%, 97.5%, and 90% respectively. Up-regulated Rex1 gene expression.
In Vivo	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM, 24 h)-treated mESCs in the presence/absence of LIF (injected in both thighs) generated teratomas in severe combined immunodeficiency (SCID) mice, which indicates that the process of mESC tumor formation in vivo is dependent on integrin interaction[1].

Molecular Formula	C24H34N8O7S
Molecular Weight	578.64100
Exact Mass	578.22700
PSA	283.50000

cyclo (Arg-Gly-Asp-d-Phe-Cys)

CYCLO(ARG-GLY-ASP-D-PHE-CYS)ACETATE SALT

cyclo(Arg-Gly-Asp-d-Phe-Cys)

Cyclo(-RGDfC), avb3 Integrin Binding Cyclic RGD Peptide

CYCLO(-ARG-GLY-ASP-D-PHE-CYS)

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