Manufacturer Provide Pharmaceutical Grade Raw Powder CAS74811-65-7 Croscarmellose Sodium
Introduction
1.Product Name: Croscarmellose Sodium
2.Other name: Sodiumcroscarmellose;CROSCARMELLOSE SODIUM;MODIFIED CELLULOSE GUM
3.CAS NO:74811-65-7
4.Purity: 55%-99.9%
5.Appearance:White Powder
6.Molecular formula: C12h20o6
7.Melting Point :>205 (lit.)
8.Density:0.999 g/cm3 at 20 °C (lit.)
9.Storage:Keep in a cool, dry, dark location
Croscarmellose sodium resolves formulators′ concerns over long-term functional stability, reduced effectiveness at high tablet hardness levels, and similar problems associated with other products developed to enhance drug dissolution. Croscarmellose sodium is a very commonly used pharmaceutical additive approved by the U.S. Food and Drug Administration. Its purpose in most tablets - including dietary supplements - is to assist the tablet in disintegrating in the gastrointestinal tract promptly. If a tablet disintegrating agent is not included, the tablet could disintegrate too slowly, in the wrong part of the intestine or not at all, thereby reducing the efficacy and bioavailability of the active ingredients.
Function
1. In the pharmaceutical industry can be used as emulsifying stabilizer of injection, as binder and filmogen of tablet. Someone through the basis and animal experiments proved that Croscarmellose Sodium is safe and reliable anticancer drug carrier.
2. Croscarmellose Sodium also can be used as flocculating agent, chelating agent, emulsifier, thickener, water-retaining agent, sizing agent, film-forming materials, widely used in electronics, pesticide, leather, plastic, printing, ceramics, daily chemical and other fields.
3. Croscarmellose Sodium is of thickening, emulsification, excipient, preservation and other functions.Can be used in drinks, biscuits, puffed food, ice cream, cakes, jellies and other foods instead of gelatin, agar, sodium alginate, xanthan gum, used in moderation for production need.
Application
The largest use of Croscarmellose Sodium is to compound soap and synthetic detergent, add about 1% of Croscarmellose Sodium in the heavy cleaner, to prevent the dirt washed out reprecipitating on the fabric. Secondly, Croscarmellose Sodium is used as suspension stabilizer of drilling fluid in petroleum industry.
1. In the detergent, Croscarmellose Sodium is used as dirt redeposition resistance agent, especially for hydrophobic synthetic fabrics, the dirt redeposition resistance effect is great.
2. Used in oil and gas drilling, sink well and other projects, in oil drilling, Croscarmellose Sodium can be used as suspension stabilizer and water-retaining agent to protect oil well. Generally, the dosage is 2.3 t for shallow well, 5.6 t for deep well.
3. In textile industry, Croscarmellose Sodium is used as thickening agent of sizing agent and dyeing agent, to improve the solubility and viscosity of sizing agent, is easy for the textile printing and hard finishing.
4. Used as anti-settling agent, emulsifier, dispersant, flatting agent, adhesive of paint, can make the paint solids evenly distributed in solvents, not to delaminate for a long-term, also widely used in the oil paint.
5. Used as flocculant to remove the calcium ion is more effective than sodium gluconate, when used as cation exchange, the exchange capacity can reach 1.6 ml/g.
Specification
Item | USP/BP/EP/CP |
Identification | Conforms |
pH | 5.0-7.0 |
Loss on drying (%) | ≤10.0 |
Na-chloride & Na-glycolate (%) | ≤0.50 |
Residue on lgnition/ Sulfated ash (%) | 14.0-28.0 |
Degree of Substitution | 0.60-0.85 |
Content of Water-soluble Material (%) | ≤10.0 |
Settling Volume (ml) | 10.0-30.0 |