Creatine Monohydrate
CAS No: 6020-87-7
Molecular Formula: C₄H₉N₃O₂·H₂O
Molecular Weight: 149.15 g/mol
1. Product Description
Creatine Monohydrate is a naturally occurring amino acid derivative, found primarily in muscle tissue. It appears as a white, crystalline powder, odorless, with a slightly bitter taste. It is widely used as a dietary supplement for improving athletic performance, muscle mass, and recovery.
2. Specifications – Food / Nutraceutical / Pharmaceutical Grade
| Item | Specification / Typical Value | Method / Notes |
|---|
| Appearance | White crystalline powder | Visual |
| Identification | Positive for creatine | USP / FCC |
| Assay (C₄H₉N₃O₂·H₂O) | ≥ 99.0 % (on dry basis) | HPLC |
| Loss on Drying (105 °C) | ≤ 12.0 % | Consistent with monohydrate |
| Residue on Ignition (Sulphated Ash) | ≤ 0.1 % | USP |
| pH (2 % solution) | 6.9 – 7.3 | 25 °C |
| Creatinine | ≤ 100 ppm | HPLC |
| Dicyandiamide | ≤ 50 ppm | HPLC |
| Dihydrotriazine | Not detectable | HPLC |
| Heavy Metals (as Pb) | ≤ 10 ppm | ICP |
| Lead (Pb) | ≤ 1 ppm | ICP |
| Arsenic (As) | ≤ 1 ppm | ICP |
| Cadmium (Cd) | ≤ 1 ppm | ICP |
| Mercury (Hg) | ≤ 0.1 ppm | ICP |
| Solubility | Freely soluble in water, clear solution | Visual |
| Microbiological Limits | Total plate count ≤ 10³ cfu/g; Yeast & Mold ≤ 10² cfu/g; E. coli, Salmonella negative | ISO / USP |
3. Specifications – Industrial / Technical Grade
| Item | Specification / Typical Value |
|---|
| Appearance | White crystalline powder |
| Assay | ≥ 98.0 % |
| Moisture | ≤ 12.0 % |
| Creatinine | ≤ 500 ppm |
| Heavy Metals (as Pb) | ≤ 20 ppm |
Typical Applications:
Raw material for feed formulations or technical uses
Non-food chemical synthesis and biochemical research
4. Typical Applications
Sports Nutrition: Strength, power, endurance supplements
Medical Nutrition: Support for muscle wasting, rehabilitation
Food & Beverage: Fortified health drinks, functional foods
Pharmaceuticals: Clinical nutrition formulations
5. Physical & Chemical Properties
Appearance: White crystalline powder
Taste: Slightly bitter
Solubility: 16 g/L at 20 °C in water
Bulk Density: 0.5 – 0.7 g/cm³
Stability: Stable under recommended storage; sensitive to moisture and high heat
6. Storage & Handling
Store in a cool, dry place
Keep container tightly closed to prevent moisture uptake
Avoid exposure to heat and direct sunlight
Handle using GMP / HACCP protocols for food use
7. Packaging
Food / Pharma Grade: 25 kg fiber drum or multi-layer paper bags with PE liner
Technical Grade: 25 kg woven bags, jumbo bags available
For more information, please visit this website:https://www.khonorchem.com
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