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| Common Name | Cinchocaine |
|---|
| CAS Number | 85-79-0 | Molecular Weight | 343.463 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 491.5±55.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H29N3O2 | Melting Point | -51 °C |
|---|
| MSDS | N/A | Flash Point | 251.1±31.5 °C |
|---|
Use of Cinchocaine
Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia.Target: Sodium ChannelDibucaine is an amide local anesthetic. Dibucaine reduced the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain [1].Dibucaine, a quaternary ammonium compound, inhibited SChE to a minimum within 2 min in a reversible manner. The inhibition was very potent. It had an IC(50) of 5.3 microM with BuTch or 3.8 microM with AcTch. The inhibition was competitive with respect to BuTch with a K(i) of 1.3 microM and a linear-mixed type (competitive/noncompetitive) with respect to AcTch with inhibition constants, K(i) and K(I) of 0.66 and 2.5 microM, respectively. Dibucaine possesses a butoxy side chain that is similar to the butryl group of BuTch and longer by an ethylene group from AcTch [2].
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 491.5±55.0 °C at 760 mmHg |
|---|
| Melting Point | -51 °C |
|---|
| Molecular Formula | C20H29N3O2 |
|---|
| Molecular Weight | 343.463 |
|---|
| Flash Point | 251.1±31.5 °C |
|---|
| Exact Mass | 343.225983 |
|---|
| PSA | 54.46000 |
|---|
| LogP | 5.29 |
|---|
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.549 |
|---|
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