D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol, a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuelae.

Appearance and properties: light yellow powder

Density: 1.41 g/cm3

Boiling point: 451.9ºC at 760 mmHg

Melting point: 163-165ºC

Flash point: 227.1ºC

Storage condition: -20ºC

Production method

It is prepared from p-nitro-α-acetamido-β-hydroxyphenylacetone by reduction, hydrolysis, neutralization and resolution.

Use

Used in the pharmaceutical industry, it is an intermediate of chloramphenicol. (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol (CAS NO.716-61-0) is used in the pharmaceutical industry, and is the intermediate of chloramphenicol .

(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol , its cas register number is 716-61-0. It also can be called D-(-)Threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol ; Levoamine ; and Chloramphenicol base . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product:  Wash mouth out with water, and get medical aid immediately.

In addition, (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol (CAS NO.716-61-0) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: oxides of nitrogen, carbon monoxide, carbon dioxide.

COMPANY PROFILE

Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.