Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate NEW

Description of Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate from Wuhan Fortuna Chemical Co.,Ltd

Specifications(COA) of Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate CAS 207915-99-9

Introduction of Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate.

Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate is a chemical compound that is often used as a reagent in organic synthesis, particularly in peptide coupling reactions. It is known for its role in facilitating the formation of amide bonds, which are crucial in the synthesis of peptides and proteins.

Chemical Structure:

Chloro-N,N,N′,N′-tetramethylformamidinium: This part of the name describes the core structure of the molecule. It consists of a formamidinium ion (a derivative of formamide) where the nitrogen atoms are substituted with methyl groups (–CH₃) and a chlorine atom is attached to the carbon.

Hexafluorophosphate (PF₆⁻): This indicates that the compound is paired with a hexafluorophosphate anion, which is a common counterion used to stabilize cationic species in organic chemistry.

Applications:

1. Peptide Synthesis:

Coupling Reagent: Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate is widely used as a coupling reagent in peptide synthesis. It facilitates the formation of amide bonds between amino acids, which are the building blocks of peptides and proteins.

Efficiency: It is valued for its efficiency and effectiveness in promoting peptide bond formation, often leading to higher yields and fewer side reactions compared to other coupling reagents.

2. Organic Synthesis:

Amide Bond Formation: Beyond peptide synthesis, this compound is also used in other organic synthesis applications where the formation of amide bonds is required.

Versatility: It can be used in various synthetic pathways, making it a versatile reagent in the toolkit of organic chemists.

3. Pharmaceutical Industry:

Drug Development: In the pharmaceutical industry, it is used in the synthesis of peptide-based drugs and other complex organic molecules. Its ability to efficiently form amide bonds makes it valuable in the development of new therapeutic agents.

Summary:

Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate is a specialized reagent used primarily in peptide synthesis and other organic synthesis applications. It facilitates the formation of amide bonds, which are essential in the construction of peptides, proteins, and various pharmaceutical compounds. Its efficiency and effectiveness make it a valuable tool in both academic and industrial chemical research.

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