Manufacturer Provide Pharmaceutical Grade CAS302-17-0 Chloral Hydrate
Introduction
Product Name: Chloral hydrate
Other Name :2,2,2-Trichloro-1,1-ethanediol;2,2,2-TRICHLOROETHANE-1,1-DIOL
C.A.S NO. :302-17-0
Assay (%)(HPLC, Basis on drying):99%
Molecular formula: C2H3Cl3O2
Appearance: White Crystal Powder
Molecular weight :165.4
Melting Point :57 °C(lit.)
Boiling Point :97 °C
Density:1.43 g/mL at 20 °C
Storage Condition: Store in cool and dry places ,keep away from strong light
Chloral hydrate is Colourless crystals with an aromatic pungent smell. The taste is spicy and bitter. The exposed air gradually evaporates, and the placement time turns yellow.Soluble in water, acetone and methyl acetone, slightly soluble in turpentine, petroleum ether, carbon tetrachloride, benzene and toluene.
Application
Chloral hydrate is used for treating sleep disorders. It may be used to prevent symptoms of alcohol withdrawal or to treat existing withdrawal symptoms. It may also be used to produce sedation or sleep before certain procedures, or to relieve anxiety due to certain procedures or substance withdrawal. It may also be used to treat other conditions as determined by your doctor.
Chloral hydrate is used for the short-term treatment of insomnia and as a sedative before minor medical or dental treatment. It was largely displaced in the mid-20th century by barbiturates and subsequently by benzodiazepines. It was also formerly used in veterinary medicine as a general anesthetic. It is also still used as a sedative prior to EEG procedures, as it is one of the few available sedatives that does not suppress epileptiform discharges.
In therapeutic doses for insomnia, chloral hydrate is effective within 20 to 60 minutes. In humans it is metabolized within 7 hours into trichloroethanol and trichloroethanol glucuronide by erythrocytes and plasma esterases and into trichloroacetic acid in 4 to 5 days. It has a very narrow therapeutic window making this drug difficult to use. Higher doses can depress respiration and blood pressure.
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