| Name | Ceftriaxone sodium hydrate |
| Description | Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. |
| In vivo | Ceftriaxone maintains stability against β-lactamase enzymes produced by many bacteria, yet the β-lactamases from B. fragilis, some Klebsiella species, P. vulgaris, and P. aeruginosa can deactivate it. Ceftriaxone sodium trihydrate exhibits broad-spectrum in vitro activity against both Gram-positive and Gram-negative bacteria, aerobes, and certain anaerobes. It is effective against Staphylococcus aureus strains, whether penicillin-sensitive or penicillin-resistant (MIC90, 2 to 8 mg/L). However, its efficacy is compromised against strains resistant to methicillin or oxacillin. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (90.69 mM)
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| Keywords | damages | inflammatory | hepatorenal | cephalosporin | Antibiotic | Ceftriaxone sodium Hydrate | Inhibitor | inhibit | third-generation | Bacterial | gram-negative | Ceftriaxone sodium hydrate | antioxidant | Ceftriaxone Sodium |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
United States
